臺北醫學大學 臺北神經醫學中心 校級神經醫學研究中心

Research Spotlight

Platelet lysates and extracellular vesicles

Nanotechnology for regenerative medicine and cell therapy

Treatment of neurodegenerative diseases and traumatic brain injury

Research Results

• 1. Liu, G.-S., Chen, H.-A., Chang, C.-Y. and 9 more (...) (2025). Platelet-derived extracellular vesicle drug delivery system loaded with kaempferol for treating corneal neovascularization. Biomaterials, 319
• 2. Back, F., Barras, A., Nyam-Erdene, A. and 7 more (...) (2025). Platelet Extracellular Vesicles Loaded Gelatine Hydrogels for Wound Care. Advanced Healthcare Materials, 14(1)
• 3. Lin, Z.-W., Chen, Y.-L., Lei, W.-L. and 7 more (...) (2025). Hierarchically structured conductive hydrogels for electrically programmable drug delivery in a diabetic wound healing electronic patch. Journal of Controlled Release, 383
• 4. Szunerits, S., Chuang, E.-Y., Yang, J.-C. and 2 more (...) (2025). Platelet extracellular vesicles-loaded hydrogel bandages for personalized wound care. Trends in Biotechnology, 43(7) 1627–1641
• 5. Pan, W.-Y., Weng, P.-W., Wu, S.-H. and 10 more (...) (2025). Intranasal delivery of epigallocatechin gallate-laden platelet extracellular vesicles for mitigating retinal glaucoma. Journal of Controlled Release, 381
• 6. Don, T.-M., Lee, K.-T., Chen, B.-Y. and 3 more (...) (2025). Physicochemical properties of bacterial cellulose/phototherapeutic polypyrrole/antibacterial chitosan composite membranes and their evaluation as chronic wound dressings. International Journal of Biological Macromolecules, 308
• 7. Hung, C.-Y., Hsueh, T.-Y., Rethi, L. and 2 more (...) (2025). Advancements in regenerative medicine: a comprehensive review of stem cell and growth factor therapies for osteoarthritis. Journal of Materials Chemistry B, 13(15) 4494–4526
• 8. Yeh, H.C., Gupta, K., Lu, Y.-H. and 5 more (...) (2025). Platelet Extracellular Vesicles as Natural Delivery Vehicles for Mitochondrial Dysfunction Therapy?. ACS Biomaterials Science and Engineering, 11(5) 2601–2621
• 9. Chen, K.-H., Wong, P.-C., Rethi, L. and 7 more (...) (2025). Bioabsorbable magnesium-based bulk metallic glass composite (BMGC) for improved medial opening wedge high tibial osteotomy in knee osteoarthritis. Journal of Orthopaedic Translation, 50 97–110
• 10. Huang, W.-Y., Pan, W.-Y., Wu, S.-H. and 2 more (...) (2025). Enhanced scar mitigation via hyperbaric oxygen therapy and immune modulation using nanoparticle-orchestrated photosynthetic chlorella in polysaccharide hydrogels. Chemical Engineering Journal, 509
• 11. Liu, M.-H., Gao, Z.-J., Huang, W.-Y. and 9 more (...) (2025). New NIR-Activated Organic Molecule-Based Nanocomposite as an Efficient Sensitizer for Photothermal and Photodynamic Therapy of Cancer. Advanced Healthcare Materials, 14(13)
• 12. Goubran, H., Ahmed, S., Ragab, G. and 2 more (...) (2025). Platelet proteomics: Clinical implications – Decoding the black box!. Transfusion and Apheresis Science, 64(1)
• 13. Lundy, D.J., Burnouf, T., Lai, J.J. and 2 more (...) (2025). Scalable technologies in the manufacture and deployment of cell-free cardiac therapies. Trends in Biotechnology, 43(11) 2786–2802
• 14. Epstein, J.S., Maryuningsih, Y., Faber, J.-C. and 2 more (...) (2025). Response to comments on inclusion of cryoprecipitate, pathogen-reduced on the WHO model lists of essential medicines for adults and children: a call for action. Blood Transfusion, 23(2) 191–192
• 15. NyamErdene, A., Le, N.T.N., Nebie, O. and 9 more (...) (2026). Platelet concentrate-derived extracellular vesicles promote adult hippocampal neurogenesis. Biomaterials, 328
• 16. Wu, S.-H., Lu, H.-T., Nguyen, H.T. and 3 more (...) (2025). Microwave-orchestrated phototherapeutic polypyrrole/soy extraction micro-complex for burn wound healing in a rodent model. Journal of Drug Delivery Science and Technology, 108
• 17. Ho, M.-H., Tsai, Y.-J., Lee, Y.-H. and 10 more (...) (2026). CCL5/RANTES signaling in inflammation dysregulation after mild traumatic brain injury. Journal of Biomedical Science, 33(1)
• 18. Goubran, H., Epstein, J., Burnouf, T. (2025). Repurposing surplus plasma and expired platelets into useful biotherapies. Transfusion and Apheresis Science, 64(6)
• 19. Quiñones, E.D., Wang, M.-H., Liu, K.-T. and 10 more (...) (2025). Corrigendum to ‘Extracellular vesicles from human adipose-derived stem cell spheroids: Characterization and therapeutic implications in diabetic wound healing’ [Mater. Today Bio Volume 29, December 2024, 101333] (Materials Today Bio (2024) 29, (S2590006424003946), (10.1016/j.mtbio.2024.101333)). Materials Today Bio, 32
• 20. Burnouf, T., Strengers, P., Busch, M.P. (2026). Beyond transfusion: Platelet-derived therapeutic products as a new frontier for blood establishments and transfusion medicine. Vox Sanguinis, 121(2) 114–123
• 21. Chen, H.T., Martino, M., Dabiri, E. and 6 more (...) (2025). Biological correlates of temperament: systematic reviews, empirical studies, and a conceptual framework linking neurotransmitter signaling, intrinsic brain activity, and the hyperthymic-depressive spectrum. Molecular Psychiatry, 30(12) 5880–5888