Neurodegenerative Disease Department Common Diseases
Disease Name | ||
---|---|---|
Cognitive impairment | Alzheimer's disease | dementia |
Parkinson's disease | cerebellar ataxia | amyotrophic lateral sclerosis (ALS) |
Huntington's disease | leukoaraiosis | degenerative spinal arthritis |
Neurodegenerative Disease Team Introduction
The Neurodegenerative Disease Team at the Taipei Neuroscience Institute focuses primarily on the diagnosis, treatment, and research of neurodegenerative diseases. In the field of neurodegenerative diseases, sometimes the etiology is associated with genetics, so this team also utilizes gene-related techniques.
Neurodegenerative diseases are becoming increasingly common in aging societies. Diseases such as dementia or Alzheimer's disease, Parkinson's disease, and cerebellar atrophy are examples of neurodegenerative diseases. The exact causes of neurodegenerative diseases are not easy to determine, but many studies suggest that acquired factors such as daily exposure to air, water, diet, and lifestyle can lead to premature degeneration of nerve cells. When nerve cells degenerate and die to a certain extent, clinical symptoms may appear.
Additionally, this team utilizes more novel diagnostic techniques. Common brain examinations and molecular imaging examinations contribute to the early diagnosis of neurodegenerative diseases in the medical field. Regarding treatment, different treatments and the selection of neuroprotective drugs can be applied to different neurodegenerative diseases, with the hope of effectively delaying the progression of neurological diseases in the future.
For the Neurodegenerative Disease Team, in terms of diagnosis, genetic testing technology has reached a mature stage, allowing for the identification of pathogenic genes as early as possible. Furthermore, imaging examinations enable healthcare professionals to detect clues related to neurodegenerative diseases before or at the onset of the disease.
Director

Yi-Chun Kuan M.D.
Director, Department of Neurodegenerative Disease, Taipei Neuroscience Institute
Attending Neurosurgeon at Taipei Medical University Shuang Ho Hospital
Specialty
Insomnia/sleep disorder/sleep apnea、Dementia、Epilepsy/seizure、Stroke/cerebral vascular disease、Headache/dizziness、General neurological disorder(restless leg syndrome, Bell's palsy, carpal tunnel syndrome etc.)
Education
- 1999-2006 M.D., School of Medicine, College of Medicine, Taipei Medical University
Experience
- 2024.04- Director, Degenerative Disease, Taipei Neuroscience Institute
- 2021.11-2022.07 Associate Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2020.08- Associate Professor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- 2017.08-2020.07 Assistant Professor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- 2014.08-2017.07 Instructor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
Member Introduction

Tu-Hsueh Yeh M.D., Ph.D.
- Vice Superintendent of Education,Taipei Neuroscience Institute
Specialty
- Parkinson’s disease and movement disorders、Neurogenetic diseases、Dementia-related neurological damage diseases、Neurofibromatosis、Movement disorders、Cerebrovascular disease
Education
- 1998-2005 Ph.D., Graduate Institute of Clinical Medical Sciences, Chang Gung University
- 1987-1994 M.D., School of Medicine, College of Medicine, Taipei Medical University
Experience
- 2024.04- Deputy Superintendent, TMU Neuroscience Research Center, Taipei Medical University, Taipei, Taiwan
- 2023.09- Director, Department of Medical Education Teaching, Taipei Medical University Hospital
- 2023.08- Director, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- Director, Degenerative Disease, Taipei Neuroscience Institute
- 2020.08-2022.09 Director, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- 2019.08-2022.09 Director, Division of Neurology, Taipei Medical University Hospital
- 2019.08- Associate Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2017.10- Associate Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2017.02- Associate Professor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- 2016.03-2017.01 Adjunct Associate Professor, Department of Medicine, Chang Gung University

Jau-Jiuan Sheu M.D
- Attending Neurologist at Taipei Medical University Hospital
Specialty
- Dementia、Memory disorders、Neurodegenerative disorders、Carpal tunnel syndrome
Education
- 1993-1995 M.P.H., Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University
- 1980-1987 M.D., School of Medicine, College of Medicine, National Taiwan University
Experience
- 2012.08- Associate Professor, Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan
- 2011.02-2012.07 Assistant Professor, Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan
- 2010.06-2011.01 Assistant Professor, School of Gerontology and Health Management, Taipei Medical University
- 2010.06-2011.01 Assistant Professor, Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan
- 2009.08-2010.05 Assistant Professor, Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan
- 1998.10-2009.07 Instructor, Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan
- 1997.09- Attending Physician, Department of Neurology, Taipei Medical University Hospital
- 1996.01-1997.08 Attending Physician, Taipei City Hospital
- 1993.10-1995.11 Attending Physician, National Taiwan University Hospital Hsin-Chu Branch
- 1992.07-1993.10 Chief Resident Physician, National Taiwan University Hospital Hsin-Chu Branch
- 1989.07-1992.06 Resident Physician, National Taiwan University Hospital

Rey-Yue Yuan M.D.
- Attending Neurologist at Taipei Medical University Hospital
Specialty
- Parkinson's disease、Movement disorder、Dementia、Headache、Neuromuscular disorders、Epilepsy
Education
- 1975-1982 M.D., School of Medicine, Taipei Medical College
Experience
- 2013.08- The Ph.D., Program for Neural Regenerative Medicine, Taipei Medicine University
- 2007.08- Associate Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2006.02- Associate Professor, Graduate Institute of Medical Sciences, Taipei Medical University

Shu-Mei Chen M.D., Ph.D.
- Attending Physician, Department of Neurosurgery, Taipei Medical University Hospital
Specialty
- Brain Tumor, Cerebral Cortical Functional Location、Endoscopic pituitary tumor resection、Epilepsy surgery、Skull base surgery、Minimally Invasive Spinal Surgery、Pediatric Neurosurgery
Education
- 2009-2019 Ph.D., Graduate Institute of Clinical Medical Sciences, Chang Gung University
- 1994-2001 M.D., School of Medicine, College of Medicine, Taipei Medical University
Experience
- 2023.11- Vice President of Teaching, Biodesign Center, Taipei Medical University
- 2020.07- Assistant Professor, Department of Surgery, School of Medicine, Taipei Medical University
- 2019.10- Visiting Staff, Taipei Medical University Hospital
- 2010-2019 Visiting Staff, Division of Neurosurgery, Taipei Municipal Wan-Fang Hospital

Ruei-Yi Tai M.D.
- Attending Neurologist at Taipei Medical University Hospital
Specialty
- Parkinson's disease、Movement Disorder、Cerebrovascular disease、Sleep disorder/Insomnia、General neurological disease
Education
- M.D., School of Medicine, College of Medicine, National Taiwan University
Experience
- Director of the Neurology Examination Room at Taipei Medical University Hospital (current)
- Resident and Chief Resident in Neurology at Taipei Medical University Hospital
- Resident in Internal Medicine at National Taiwan University Hospital
- Intern at National Taiwan University Hospital
- Member of the Taiwan Movement Disorder Society
- Member of the Taiwan Society of Sleep Medicine

Hsin-Chien Lee M.D.
- Director and Attending Psychiatrist at Taipei Medical University Hospital
Specialty
- Sleep Medicine、General psychiatry
Education
- 2002-2004 M.P.H., School of Public Health, Columbia University
- 1987-1994 M.D., School of Medicine, Taipei Medical College
Experience
- 2024.04- Director, Division of Sleep Disorders, Taipei Neuroscience Institute
- 2023.02- Vice Dean, College of Humanities and Social Sciences, Taipei Medical University
- 2021.08- Director, Department of Psychiatry, Taipei Medical University Hospital
- 2020.02- Associate Professor, Masters and Ph.D. programs of Mind Brain and Consciousness, Taipei Medical University
- 2019.08- Associate Professor, Professional Master Program in Artificial Intelligence in Medicine, College of Medicine, Taipei Medical University
- 2016.11- Director, Research Center of Sleep Medicine, Taipei Medical University
- 2014.08- Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2011.08- Associate Professor, Department of Psychiatry, School of Medicine, Taipei Medical University
- 2008- Visiting Staff & Chair, Department of Psychiatry, Taipei Medical University Shuang Ho Hospital
- 1999.07- Attending Physician, Taipei Medical University Hospital
- 2020.08-2024.01 Director, Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University
- 22016.09-2016.10 Director, Department of Humanities in Medicine, Taipei Medical University

Jia-Ying Sung M.D., Ph.D.
- Attending Neurologist, Taipei Municipal Wan-Fang Hospital
Specialty
- Neuromuscular disease、Dystonia、Sleep disorder
Education
- 2001-2004 Ph.D., Neurology, Graduate School of Medicine and Pharmacy, Chiba University
- 1988-1995 M.D., School of Medicine, College of Medicine, Taipei Medical University
Experience
- 2024.03 Director, Division of Peripheral Nervous Disorders, Taipei Neuroscience Institute
- Director, Sleep Laboratory, Taipei Municipal Wan-Fang Hospital
- 2023.02- Professor, Department of Neurology, School of Medicine, Taipei Medical University
- 2019.08-2023.10 Director, Department of Neurology, Taipei Municipal Wan-Fang Hospital
- 2014.08-2023.01 Associate Professor, Department of Neurology, School of Medicine, Taipei Medical University

Chin-I Chen M.D.
- Attending Neurologist, Taipei Municipal Wan-Fang Hospital
Specialty
- Cerebrovascular disease、Dementia、Parkinson's disease
Education
- 2022.01-2022.05 Stanford University
- 1985-1992 M.D., School of Medicine, College of Medicine, Taipei Medical University
Experience
- 2024.01-2024.03 Vice Director, Department of Medical Administration, Taipei Neuroscience Institute
- Vice Director, Secretariat, Taipei Neuroscience Institute
- 2021.04- Director, Department of Business Development, Taipei Municipal Wan-Fang Hospital
- Director, Department of Preventive & Social Medicine, Taipei Municipal Wan-Fang Hospital
- 2017.09- Assistant Professor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University

Hsing-Yu Weng, M.D.
- Attending Neurologist, Taipei Municipal Wan-Fang Hospital
Specialty
- Headache、Chronic pain、Cerebrovascular disease、Degenerative neurological diseases
Education
- 2005-2013 Ph.D., Graduate Institute of Clinical Medicine, Taipei Medical University
- 1987-1994 M.D., School of Medicine, National Yang-Ming University
Experience
- 2014.06 Assistant professor, Department of Neurology, Taipei Medical University
- 2009.02-2014.06 Clinical Instructor, Department of Neurology, Taipei Medical University

Chih-Shan Huang M.D.
- Director of Neurology, Taipei Municipal Wan-Fang Hospital
Specialty
- Sleep disorders、Cerebrovascular disease、Dementia
Education
- 1998-2005 M.D. Taipei Medical University, Taipei, Taiwan
Experience
- 2023.11- Acting Director, Department of Neurology, Taipei Municipal Wan-Fang Hospital

Hung-Ju Chen M.D.
- Attending Neurologist at Taipei City Wan Fang Hospital
Specialty
- Dementia、Cerebrovascular disease、General neurological disorders、Treatment and care of acute and chronic diseases in the elderly
Education
- M.D., College of Medicine, Taipei Medical University
Experience
- Adjunct Attending Neurologist at the Department of Neurology, Ministry of Health and Welfare Le Sheng Hospital
- Resident and Chief Resident in Neurology at Taipei City Wan Fang Hospital

Jowy Tani M.D., Ph.D.
- Attending Neurologist, Taipei Municipal Wan-Fang Hospital
Specialty
- Sleep disorders、Dementia、Cerebrovascular disease
Education
- 2014-2021 Ph.D., The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2002-2008 M.D., Faculty of Medicine, Universitas Indonesia
Experience
- 2024.01- Joint-Appointment Assistant Professor, Ph.D. Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University
- 2022.02- Assistant Professor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- 2021.08- Deputy Director, Biomedical Innovation Center, Wan Fang Hospital, Taipei Medical University
- 2021.05- Deputy Secretary General, Taiwan Neurological Society
- 2020.03- CEO, Taipei Medical University BioMed Accelerator
- 2015.06- Attending Neurologist, Wan Fang Hospital, Taipei Medical University
- 2021.10-2023.11 Vice President of Teaching, Biodesign Center, Taipei Medical University
- 2020 Stanford Biodesign Global Faculty Fellow, Byers Center for Biodesign, Stanford University
- 2017-2018 Berkeley-Taiwan Biomedical (BTB) Fellow, UC Berkeley College of Engineering
- 2013-2015 Fellow in Sleep Medicine and Neurocritical Care, Wan Fang Hospital, Taipei Medical University

Hsin-Ying Lin M.D., M.S.
- Attending Neurologist, Taipei Municipal Wan-Fang Hospital
Specialty
- Surgical treatment for Parkinson’s disease, shoulder and neck pain, and lower back pain、Spinal surgery, neuroma surgery, osteoporosis treatment、Compression fracture treatment, head trauma treatment, stroke treatment, peripheral neuropathy treatment
Education
- 2018 M.S., Graduate Institute of Prevention and Control, Taipei Medical University
- MD, College of Medicine, Tzu Chi University
Experience
- Director of the Neurosurgery Ward and Attending Physician, Wanfang Hospital
- Advanced Studies in Movement Disorders, University of London, UK
- Chief Resident in Neurosurgery, Wanfang Hospital
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Chien-Tai Hong M.D., Ph.D.
- Attending Neurologist at Taipei Medical University Shuang Ho Hospital
Specialty
- Parkinson's disease、Other movement disorders
Education
- 011-2014 Ph.D., Philosophy, University College London
- 1998-2005 M.D., School of Medicine, College of Medicine, Taipei Medical University
Experience
- 2024.03 Acting Director, Degenerative Disease, Taipei Neuroscience Institute
- 2024.01- Director, Department of Neurology, Taipei Medical University Shuang Ho Hospital
- 2023.08- Professor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- 2022.10-2023.03 Director, Degenerative Disease, Taipei Neuroscience Institute
- 2022.08- Director, Department of Medical Research, Taipei Medical University Shuang Ho Hospital, Ministry of Health and Welfare
- Attending Physician, Taipei Medical University Shuang Ho Hospital, Ministry of Health and Welfare
- 2020.08-2023.08 Associate Professor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- 2016.11-2020.07 Assistant Professor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- Attending Physician, Far Eastern Memorial Hospital
- Resident Physician, En Chu Kong Hospital

Tzu-Hsiang Ko M.D.
- Attending Neurologist at Taipei Medical University Shuang Ho Hospital
Specialty
- Movement Disorders、Parkinson's Disease、Peripheral Neuromuscular Disorders、General Neurological Disorders
Education
- Department of Medicine, National Taiwan University
Experience
- Resident、Chief Resident, Department of Neurology, Shuang Ho Hospital
- Attending Physician, Department of Neurology, Taitung Hospital, Ministry of Health and Welfare
- Attending Physician, Department of Neurology, Kinmen Hospital, Ministry of Health and Welfare

Po-Chih Chen M.D., Ph.D.
- Attending Neurologist at Taipei Medical University Shuang Ho Hospital
Specialty
- Headache, stroke, insomnia、Neck-shoulder pain、Sciatic nerve pain、Parkinson disease
Education
- 2011-2020 Ph.D., The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 1998-2005 M.D., School of Medicine, College of Medicine, Taipei Medical University
Experience
- 2022.03- Assistant Professor, Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University
- 2009.08-2011.03 Attending Physician, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
- 2009.04-2009.07 Resident Physician, Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare
- 2005.08-2009.03 Resident Physician, Taipei Municipal Wan-Fang Hospital

Wei-Lun Lo M.D., Ph.D.
- Attending Neurosurgeon at Taipei Medical University Shuang Ho Hospital
Specialty
- Movement disorder surgery (Parkinson's disease and primary tremors) - deep brain stimulation, high-frequency thermocoagulation, etc.、Epilepsy surgery - temporal lobectomy, deep electrode implantation monitoring, vagal nerve stimulation, etc.、Chronic pain surgery - nerve block surgery, spinal extradural separation, dorsal root nerve entry block, spinal cord stimulation.、Head and neck and face pain surgery (migraine, trigeminal neuralgia, clustered headache, etc.) - Gamma knife stereotactic radiosurgery, posterior occipital nerve stimulation, etc.、Brain Tumors - Glioma, Meningioma, etc
Education
- 2015-2020 Ph.D., The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2010-2016 M.D., School of Medicine, College of Medicine, Taipei Medical University
Experience
- 2024.04- Vice Director, Department of Medical Administration, Taipei Neuroscience Institute
- Attending Physician, Taipei Medical University Shuang Ho Hospital, Ministry of Health and Welfare
- 2021.06- Assistant Professor, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University

Li-Kai Huang M.D.
- Attending Neurologist at Taipei Medical University Shuang Ho Hospital
Specialty
- Dementia、Stroke、Movement Disorder、General Neurological Disease
Education
- 2000-2008 MD, China Medical University, Taiwan
- 2009-2013 Resident, Dept. of Neurology , Taipei Medical University Shuang Ho Hospital
- 2013-2014 Fellowship, Dept. of Neurology ,Taipei Medical University Shuang Ho Hospital
- 2014- Attending physician, Dept. of Neurology ,Taipei Medical University Shuang Ho Hospital
Experience
- 2014- Attending physician, Dept. of Neurology ,Taipei Medical University Shuang Ho Hospital

Shu-Ping Chao M.D.
- Attending Neurologist at Taipei Medical University Shuang Ho Hospital
Specialty
- Dementia、Cerebrovascular disease、Dizziness、Headache
Education
- 2000.07-2006.06 M.D., School of medicine, National Defense Medical Center, Taipei, Taiwan
Experience
- 2015- Attending Physician, Department of neurology, Taipei Medical University Shuang Ho Hospital
- 2013 -2015 Attending Physician, Department of neurology, Wan Fang Medical Center
- 2011-2013 Fellow , Department of neurology, Wan Fang Medical Center
- 2007-2011 Resident, Department of neurology, Wan Fang Medical Center

Chaur-Jong Hu M.D.
- Attending Neurologist at Taipei Medical University Shuang Ho Hospital
Specialty
- Headache, dizziness, neuralgia、Stroke and other cerebral vascular diseases、Epilepsy, limb shakiness、Intellectual regression or dementia、Parkinson disease or gait abnormality、Asphyxia and other impaired consciousness、Limb numbness or peripheral neuropathy, etc.
Education
- 1983-1990 M.D, School of Medicine, Taipei Medical College
Experience
- 2022.02- Professor, Master Program in Clinical Genomics and Proteomics, Taipei Medical University
- 2021.08- Deputy Director, College of Medicine, Taipei Medical University
- 2018.01-2024.03 Deputy Superintendent, TMU Neuroscience Research Center, Taipei Medical University, Taipei, Taiwan
- 2017.08- Director, Ph.D. Program in Medical Neuroscience, Taipei Medical University, Taipei, Taiwan
- 2017.08- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2017.08- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2016.08-2019.07 Vice Superintendent, Taipei Medical University Shuang Ho Hospital
- 2014.08-2020.07 Director, Department of Neurology, School of Medicine, Taipei Medical University, Taipei, Taiwan

Tian-Shin Yeh M.D., Ph.D.
- Attending Physician, Department of Rehabilitation Medicine, Taipei City Wan-Fang Hospital
Specialty
- General rehabilitation、Geriatrics、Musculoskeletal、Ultrasound examination、Stroke rehabilitation、Neurological rehabilitation
Education
- 2016-2020 Ph.D. in Epidemiology (Program in Population Health Sciences), Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University
- 2014-2016 M.M.Sc. (Master of Medical Science), Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University
- 2002-2009 M.D., School of Medicine, College of Medicine, Fu Jen Catholic University
Experience
- 2022.08- Assistant Professor, Department of Physical Medicine and Rehabilitation, School of Medicine, Taipei Medical University
- 2022.06- Visiting Scientist, Department of Nutrition, Harvard T.H. Chan School of Public Health, Harvard University
- 2021.06-2022.06 Postdoctoral Fellow, Harvard-Oxford Program in Epidemiology, Harvard T.H. Chan School of Public Health and Oxford University
- 2020.06-2021.05 Postdoctoral Fellow, Department of Nutrition, Harvard T.H. Chan School of Public Health, Harvard University
- 2018.09-2018.12 Teaching Fellow, Ergonomics and Human Factors, Harvard University
- 2018.01-2018.05 Teaching Fellow, Human Pathophysiology, Harvard University
- 2013.07-2016.07 Attending Physician, Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital Yun-Lin Branch