臺北醫學大學 臺北神經醫學中心 校級神經醫學研究中心

研究亮點

Platelet lysates and extracellular vesicles

Nanotechnology for regenerative medicine and cell therapy

Treatment of neurodegenerative diseases and traumatic brain injury

研究成果

• 1. Livkisa, D., Chang, T.-H., Burnouf, T. and 6 more (...) (2024). Extracellular vesicles purified from serum-converted human platelet lysates offer strong protection after cardiac ischaemia/reperfusion injury. Biomaterials, 306
• 2. Lin, J.-C., Kaswan, K., Chatterjee, S. and 13 more (...) (2024). CuO NWs boosted triboelectric microfluidic nanosensor functionalized by collagen-protein interactions for real-time platelet count monitoring. Chemical Engineering Journal, 490
• 3. Wu, S.-H., Rethi, L., Pan, W.-Y. and 2 more (...) (2024). Emerging horizons and prospects of polysaccharide-constructed gels in the realm of wound healing. Colloids and Surfaces B: Biointerfaces, 235
• 4. Burnouf, T., Epstein, J., Faber, J.-C. and 1 more (...) (2024). Stepwise options for preparing therapeutic plasma proteins from domestic plasma in low- and middle-income countries. Vox Sanguinis, 119(2) 102–109
• 5. Delila, L., Nebie, O., Le, N.T.N. and 9 more (...) (2024). Neuroprotective effects of intranasal extracellular vesicles from human platelet concentrates supernatants in traumatic brain injury and Parkinson’s disease models. Journal of Biomedical Science, 31(1)
• 6. Le, N.T.N., Han, C.-L., Delila, L. and 6 more (...) (2024). Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration. APL Bioengineering, 8(2)
• 7. Lin, C.-W., Liu, T.-H., Chen, V. and 3 more (...) (2024). Synergistic potential of gellan gum methacrylate and keratin hydrogel for visceral hemostasis and skin tissue regeneration. Materials Today Bio, 27
• 8. Chuang, E.-Y., Lin, Y.-C., Huang, Y.-M. and 8 more (...) (2024). Biofunctionalized hydrogel composed of genipin-crosslinked gelatin/hyaluronic acid incorporated with lyophilized platelet-rich fibrin for segmental bone defect repair. Carbohydrate Polymers, 339
• 9. Chen, S.-H., Wang, H.-W., Yang, P.-C. and 11 more (...) (2024). Schwann cells acquire a repair phenotype after assembling into spheroids and show enhanced in vivo therapeutic potential for promoting peripheral nerve repair. Bioengineering and Translational Medicine, 9(2)
• 10. Liu, K.-T., Wang, P.-W., Hsieh, H.-Y. and 14 more (...) (2024). Site-specific thrombus formation: advancements in photothrombosis-on-a-chip technology. Lab on a Chip, 24(14) 3422–3433
• 11. Don, T.-M., Hong, Y.-T., Jheng, P.-R. and 2 more (...) (2024). Improved camptothecin encapsulation and efficacy by environmentally sensitive block copolymer/chitosan/fucoidan nanoparticles for targeting lung cancer cells. International Journal of Biological Macromolecules, 277
• 12. Rethi, L., Wong, C.-C., Liu, W.-J. and 4 more (...) (2024). Self-adaptable calcium-based bioactive phosphosilicate-infused gelatin-hyaluronic hydrogel for orthopedic regeneration. International Journal of Biological Macromolecules, 256
• 13. Chen, Y.-C., Chuang, E.-Y., Tu, Y.-K. and 2 more (...) (2024). Human platelet lysate-cultured adipose-derived stem cell sheets promote angiogenesis and accelerate wound healing via CCL5 modulation. Stem Cell Research and Therapy, 15(1)
• 14. Yeh, W.-T., Yu, E.Y.-L., Lu, Y.-H. and 3 more (...) (2024). Bioprocessing of human platelet concentrates to generate lysates and extracellular vesicles for therapeutic applications. MethodsX, 13
• 15. Ho, M.-H., Tsai, Y.-J., Chen, C.-Y. and 6 more (...) (2024). CCL5 is essential for axonogenesis and neuronal restoration after brain injury. Journal of Biomedical Science, 31(1)
• 16. Burnouf, T., Epstein, J., Faber, J.-C. and 1 more (...) (2024). Response to comments from the International Patient Organization for Primary Immunodeficiencies on ‘Stepwise options for preparing therapeutic plasma proteins from domestic plasma in low- and middle-income countries’. Vox Sanguinis, 119(9) 1023–1024
• 17. Quiñones, E.D., Wang, M.-H., Liu, K.-T. and 10 more (...) (2024). Extracellular vesicles from human adipose-derived stem cell spheroids: Characterization and therapeutic implications in diabetic wound healing. Materials Today Bio, 29